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Peptide 46

Product Name
Peptide 46
CAS No.
192122-40-0
Chemical Name
Peptide 46
Synonyms
PEPTIDE 46;P53 (361-382) (HUMAN);CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN);p53 (361-382) (huMan), Cellular TuMor Antigen p53 (361-382) (huMan);H-GLY-SER-ARG-ALA-HIS-SER-SER-HIS-LEU-LYS-SER-LYS-LYS-GLY-GLN-SER-THR-SER-ARG-HIS-LYS-LYS-OH;Glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-L-lysine;L-Lysine, glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-
CBNumber
CB4323244
Molecular Formula
C100H174N40O31
Formula Weight
2432.7
MOL File
192122-40-0.mol
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Peptide 46 Property

Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
-15°C
InChIKey
KCXVFJXIDLDWKX-JEWKGGOJSA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
ATG0000935
Product name
CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN)
Purity
95.00%
Packaging
5MG
Price
$496.31
Updated
2021/12/16
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Peptide 46 Chemical Properties,Usage,Production

Description

Peptide 46, a synthetic 22-mer peptide derived from the p53 C-terminal domain, can restore the growth suppressor function of mutant p53 proteins in human tumor cells. The sequence of peptide 46, which corresponds to residues 361 to 382 in the p53 C terminus, is (in one-letter code) GSRAHSSHLKSKKGQSTSRHKK[1]. Teptide 46, the only C-terminal peptide that can activate the specific DNA binding of p53, changed the mobility of the core domain, whereas the other C-terminal peptides did not. Conversely, the mobility of the C-terminal domain protein was shifted upon incubation with the core domain protein.

References

[1] G Selivanova. “Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.” Molecular and Cellular Biology 19 5 (1999): 3395–402.

Peptide 46 Preparation Products And Raw materials

Raw materials

Preparation Products

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Peptide 46 Suppliers

Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
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View Lastest Price from Peptide 46 manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
PEPTIDE 46 192122-40-0
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2024-01-11

192122-40-0, Peptide 46Related Search:


  • PEPTIDE 46
  • P53 (361-382) (HUMAN)
  • p53 (361-382) (huMan), Cellular TuMor Antigen p53 (361-382) (huMan)
  • H-GLY-SER-ARG-ALA-HIS-SER-SER-HIS-LEU-LYS-SER-LYS-LYS-GLY-GLN-SER-THR-SER-ARG-HIS-LYS-LYS-OH
  • CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN)
  • Glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-L-lysine
  • L-Lysine, glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-
  • 192122-40-0